Penn State Health Holy Spirit Medical Center has been serving the greater Harrisburg region with high-quality, ethically guided and patient-focused health care services since 1963. This 307-bed community hospital in East Pennsboro Township provides outpatient and inpatient diagnostic, medical and surgical services. Holy Spirit Medical Center joined Penn State Health in 2020.

Nationally accredited for its centers of excellence in cardiac care, atrial fibrillation, heart attack (STEMI), heart failure, stroke, diabetes and knee and hip replacement, Holy Spirit Medical Center is also certified as an Advanced Primary Stroke Center by The Joint Commission, in conjunction with the American Heart Association and the American Stroke Association.

Its Level II Trauma Center provides around-the-clock complex critical care for people with life-threatening injuries.